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Cell Signal Transduction Research Antibodies
KIF2C (phospho Ser95) Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight81313Da
Protein NameKinesin-like protein KIF2C
Human Gene Id11004
Human Swiss Prot NoQ99661
Mouse Gene Id73804
Mouse Swiss Prot NoQ922S8
SpecificityPhospho-KIF2C (S95) Polyclonal Antibody detects endogenous levels of KIF2C protein only when phosphorylated at S95.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKIF2C; KNSL6; Kinesin-like protein KIF2C; Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK
Observed Band(KD)80
Functionfunction:Present throughout the cell cycle, associates with centromeres at early prophase, and remains associated with the centromere until after telophase.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family.,similarity:Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.,similarity:Contains 1 kinesin-motor domain.,subunit:Interacts with CENPH.,tissue specificity:Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas.,
Subcellular Locationchromosome, centromeric region,kinetochore,condensed chromosome kinetochore,nucleus,cytosol,kinesin complex,microtubule,cytoplasmic microtubule,microtubule cytoskeleton,membrane,microtubule plus-end,
ExpressionBrain,Epithelium,Kidney,T-cell,Testis,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human KIF2C around the phosphorylation site of Ser95. AA range:61-110
Gene NameKIF2C
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundkinesin family member 2C(KIF2C) Homo sapiens This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-60566-Conjugate. Price: $485 / Size: 100μl.
E20-60566-FITC$485 / 100μlE20-60566-Biotin$485 / 100μlE20-60566-HRP$485 / 100μlE20-60566-AP$485 / 100μlE20-60566-AF350$485 / 100μlE20-60566-AF405M$485 / 100μlE20-60566-AF488$485 / 100μlE20-60566-AF514$485 / 100μlE20-60566-AF532$485 / 100μlE20-60566-AF555$485 / 100μlE20-60566-AF568$485 / 100μlE20-60566-AF405S$485 / 100μlE20-60566-AF405L$485 / 100μlE20-60566-AF546$485 / 100μlE20-60566-AF594$485 / 100μlE20-60566-AF610$485 / 100μlE20-60566-AF635$485 / 100μlE20-60566-AF647$485 / 100μlE20-60566-AF680$485 / 100μlE20-60566-AF700$485 / 100μlE20-60566-AF750$485 / 100μlE20-60566-AF790$485 / 100μlE20-60566-APC$485 / 100μlE20-60566-PE$485 / 100μlE20-60566-Cy3$485 / 100μlE20-60566-Cy5$485 / 100μlE20-60566-Cy5.5$485 / 100μlE20-60566-Cy7$485 / 100μlE20-60566-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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