World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies

C/EBP α (phospho Thr230) Polyclonal Antibody

E20-60463Cite ID: EN0049389DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight37575 Da
Protein NameCCAAT/enhancer-binding protein alpha
Human Gene Id1050
Human Swiss Prot NoP49715
Mouse Gene Id12606
Mouse Swiss Prot NoP53566
Rat Gene Id24252
Rat Swiss Prot NoP05554
SpecificityPhospho-C/EBP α (T230) Polyclonal Antibody detects endogenous levels of C/EBP α protein only when phosphorylated at T230.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCEBPA; CCAAT/enhancer-binding protein alpha; C/EBP alpha
Observed Band(KD)42
Functionfunction:C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP beta and gamma. Interacts with UBN1. Interacts with HBV protein X.,
Subcellular Locationnucleus,nucleolus,RNA polymerase II transcription factor complex,
ExpressionLiver,Pancreas,Umbilical cord,White Matter pool- 5 brain tissues- f
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized phospho-peptide around the phosphorylation site of human C/EBP α (phospho Thr230)
Gene NameCEBPA
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundCCAAT/enhancer binding protein alpha(CEBPA) Homo sapiens This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],

Conjugated Antibody

This product is also available conjugated. Format: E20-60463-Conjugate. Price: $485 / Size: 100μl.

E20-60463-FITC$485 / 100μlE20-60463-Biotin$485 / 100μlE20-60463-HRP$485 / 100μlE20-60463-AP$485 / 100μlE20-60463-AF350$485 / 100μlE20-60463-AF405M$485 / 100μlE20-60463-AF488$485 / 100μlE20-60463-AF514$485 / 100μlE20-60463-AF532$485 / 100μlE20-60463-AF555$485 / 100μlE20-60463-AF568$485 / 100μlE20-60463-AF405S$485 / 100μlE20-60463-AF405L$485 / 100μlE20-60463-AF546$485 / 100μlE20-60463-AF594$485 / 100μlE20-60463-AF610$485 / 100μlE20-60463-AF635$485 / 100μlE20-60463-AF647$485 / 100μlE20-60463-AF680$485 / 100μlE20-60463-AF700$485 / 100μlE20-60463-AF750$485 / 100μlE20-60463-AF790$485 / 100μlE20-60463-APC$485 / 100μlE20-60463-PE$485 / 100μlE20-60463-Cy3$485 / 100μlE20-60463-Cy5$485 / 100μlE20-60463-Cy5.5$485 / 100μlE20-60463-Cy7$485 / 100μlE20-60463-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.