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Cell Signal Transduction Research Antibodies
TIP60 (phospho Ser86) Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight:58582 Da
Protein NameHistone acetyltransferase KAT5
Human Gene Id10524
Human Swiss Prot NoQ92993
Mouse Gene Id81601
Mouse Swiss Prot NoQ8CHK4
SpecificityPhospho-TIP60 (S86) Polyclonal Antibody detects endogenous levels of TIP60 protein only when phosphorylated at S86.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKAT5; HTATIP; TIP60; Histone acetyltransferase KAT5; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein
Observed Band(KD)65
Functionnegative regulation of transcription from RNA polymerase II promoter, regulation of cytokine production, negative regulation of cytokine production, DNA metabolic process, DNA repair, double-strand break repair, chromatin organization, chromatin assembly or disassembly, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid acetylation, response to DNA damage stimulus,DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,intracellular signaling cascade, negative regulation of biosynthetic process, positive regulation of biosynthetic process,regulation of specific transcription from RNA polymerase II promoter, negative regulation of specific transcription from RNA polymerase II promoter, positive regulation of macromolecule biosynthetic process, neg
Subcellular LocationSwr1 complex,nucleus,nucleoplasm,transcription factor complex,nucleolus,Piccolo NuA4 histone acetyltransferase complex,NuA4 histone acetyltransferase complex,perinuclear region of cytoplasm,
ExpressionBrain,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human TIP60 around the phosphorylation site of Ser86. AA range:52-101
Gene NameKAT5
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundlysine acetyltransferase 5(KAT5) Homo sapiens The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-60342-Conjugate. Price: $485 / Size: 100μl.
E20-60342-FITC$485 / 100μlE20-60342-Biotin$485 / 100μlE20-60342-HRP$485 / 100μlE20-60342-AP$485 / 100μlE20-60342-AF350$485 / 100μlE20-60342-AF405M$485 / 100μlE20-60342-AF488$485 / 100μlE20-60342-AF514$485 / 100μlE20-60342-AF532$485 / 100μlE20-60342-AF555$485 / 100μlE20-60342-AF568$485 / 100μlE20-60342-AF405S$485 / 100μlE20-60342-AF405L$485 / 100μlE20-60342-AF546$485 / 100μlE20-60342-AF594$485 / 100μlE20-60342-AF610$485 / 100μlE20-60342-AF635$485 / 100μlE20-60342-AF647$485 / 100μlE20-60342-AF680$485 / 100μlE20-60342-AF700$485 / 100μlE20-60342-AF750$485 / 100μlE20-60342-AF790$485 / 100μlE20-60342-APC$485 / 100μlE20-60342-PE$485 / 100μlE20-60342-Cy3$485 / 100μlE20-60342-Cy5$485 / 100μlE20-60342-Cy5.5$485 / 100μlE20-60342-Cy7$485 / 100μlE20-60342-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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