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PTPα (phospho Tyr798) Polyclonal Antibody
Datasheet
Catalog Number:
E20-60317Amount:
100ulSwiss-Prot No.:
P18433/P18052/Q03348Molecular Weight:
90600Price:
225$Applications:
WB,ELISAReactivity:
Human,Mouse,Rat,MonkeyPurification:
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from humanPTPRA around the phosphorylation site of Tyr798. AA range:753-802Specificity/Sensitivity:
Phospho-PTPα (Y798) Polyclonal Antibody detects endogenous levels of PTPαprotein only when phosphorylated at Y798.Storage/Stability:
-20°C/1 yearSource:
Polyclonal, RabbitGene Name:
PTPRADilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other
- Western blot analysis of lysates from HeLa cells treated with serum 20% 15', using PTPRA Antibody. The lane on the right is blocked with the phospho peptide.
Background:
protein tyrosine phosphatase, receptor type A(PTPRA) Homo sapiens Theprotein encoded by this gene is a member of the protein tyrosine phosphatase
(PTP) family. PTPs are known to be signaling molecules that regulate a variety of
cellular processes including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. This PTP contains an extracellular domain, a single
transmembrane segment and two tandem intracytoplasmic catalytic domains, and
thus represents a receptor-type PTP. This PTP has been shown to
dephosphorylate and activate Src family tyrosine kinases, and is implicated in the
regulation of integrin signaling, cell adhesion and proliferation. Three alternatively
spliced variants of this gene, which encode two distinct isoforms, have been
reported. [provided by RefSeq, Jul 2008]Gene ID:
5686/19262Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Cellular localization:
intracellular,plasma membrane,integral component of plasmamembrane,integral component of membrane,receptor complex,extracellularexosome,Expression:
Brain,Epithelium,Kidney,Lymph node,Skin
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