4E-BP1 (phospho Thr69) Polyclonal Antibody

Name: 4E-BP1 (phospho Thr69) Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-60003
Price: 225 USD
Availability: InStock

E20-60003Cite ID: EN0048929Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight12449Da

Protein NameEukaryotic translation initiation factor 4E-binding protein 1

Mouse Gene Id13685

Rat Gene Id116636

Rat Swiss Prot NoQ62622

SpecificityPhospho-4E-BP1 (T69) Polyclonal Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at T69.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameEIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

Observed Band(KD)12

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from mouse 4E-BP1 around the phosphorylation site of Thr69. AA range:35-84

Gene NameEIF4EBP1

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

BackgroundEIF4EBP1 encodes one member of a family of translation repressor proteins. The eukaryotic translation initiation factor 4E binding protein 1 directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-60003-Conjugate. Price: $485 / Size: 100μl.

E20-60003-FITC$485 / 100μlE20-60003-Biotin$485 / 100μlE20-60003-HRP$485 / 100μlE20-60003-AP$485 / 100μlE20-60003-AF350$485 / 100μlE20-60003-AF405M$485 / 100μlE20-60003-AF488$485 / 100μlE20-60003-AF514$485 / 100μlE20-60003-AF532$485 / 100μlE20-60003-AF555$485 / 100μlE20-60003-AF568$485 / 100μlE20-60003-AF405S$485 / 100μlE20-60003-AF405L$485 / 100μlE20-60003-AF546$485 / 100μlE20-60003-AF594$485 / 100μlE20-60003-AF610$485 / 100μlE20-60003-AF635$485 / 100μlE20-60003-AF647$485 / 100μlE20-60003-AF680$485 / 100μlE20-60003-AF700$485 / 100μlE20-60003-AF750$485 / 100μlE20-60003-AF790$485 / 100μlE20-60003-APC$485 / 100μlE20-60003-PE$485 / 100μlE20-60003-Cy3$485 / 100μlE20-60003-Cy5$485 / 100μlE20-60003-Cy5.5$485 / 100μlE20-60003-Cy7$485 / 100μlE20-60003-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.