Form Or Antibody
Form of Antibodyname:HSP90 α Monoclonal Antibody
Gene NameHSP90AA1Protein Name:Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Renal carcinoma antigen NY-REN-38)
Human Gene Id:3320
Human Swiss Prot No:P07900
Mouse Swiss Prot No:P07901
Rat Swiss Prot No:P82995
ImmunogenSynthesized peptide derived from the C-terminal region of human HSP90A. at AA range: 660-740
Specificty Sensitivity
Specificity/SensitivityThe antibody detects endogenous HSP90 α protein
Product Information
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Storage/StabilityStability:-20°C/1 yearOther Name:Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Renal carcinoma antigen NY-REN-38)
Observed Band(KD):95
Backgroundheat shock protein 90 alpha family class A member 1(HSP90AA1) Homo sapiens The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].Function:caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,function:Molecular chaperone.,function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV., subunit: Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.
Cellular localizationextracellular region,nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane, cell surface, membrane,basolateral plasma membrane,apical plasma membrane,extracellular matrix, brush border membrane.Expression:Adult brain,Brain,Brain cortex,Breast.