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CD23 Monoclonal Antibody
Datasheet
Catalog Number:
E20-53082Amount:
100ulApplications:
FCM;ELISAReactivity:
Human;Purification:
Affinity purificationImmunogen:
Purified recombinant fragment of human CD23 expressed in E. Coli.Source:
Monoclonal, Mouse
- Flow cytometric analysis of Raji cells using CD23 Monoclonal Antibody (green) and negative control (purple).
Gene Name:
FCER2Dilution:
Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.Background:
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],Protein Name:
Low affinity immunoglobulin epsilon Fc receptorHuman Gene Id:
2208Human Swiss Prot No:
P06734Mouse Swiss Prot No:
P20693Specificity:
CD23 Monoclonal Antibody detects endogenous levels of CD23 protein.Formulation:
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.Storage Stability:
-20°C/1 yearOther Name:
FCER2; CD23A; CLEC4J; FCE2; IGEBF; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD antigen CD23References:
1. J Cutan Pathol. 2009 Feb;36(2):206-10. 2. Environ Mol Mutagen. 2009 May;50(4):285-90.Function:
function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form.,Subcellular Location:
Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Also exists as a soluble excreted form, sCD23.
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