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CD2 Monoclonal Antibody(3F3)
Datasheet
Catalog Number:
E20-53069Amount:
100ulMolecular Weight:
39448DaApplications:
IHC-p;IF(paraffin section)Reactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.Immunogen:
Synthetic Peptide of CD2Source:
Monoclonal, MouseGene Name:
CD2Dilution:
IHC: 1:200
- Immunohistochemical analysis of paraffin-embedded Human-colon tissue. 1,CD2 Monoclonal Antibody(3F3) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.
Background:
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],Protein Name:
T-cell surface antigen CD2Human Gene Id:
914Human Swiss Prot No:
P06729Mouse Gene Id:
12481Mouse Swiss Prot No:
P08920Rat Gene Id:
497761Rat Swiss Prot No:
P08921Specificity:
The antibody detects endogenous CD2 proteins.Formulation:
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.Storage Stability:
-20°C/1 yearOther Name:
CD2; SRBC; T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2Function:
function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,Subcellular Location:
Cell membrane ; Single-pass type I membrane protein .Expression:
Expressed in natural killer cells (at protein level).
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