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MAP2 Monoclonal Antibody(7D4)
Datasheet
Catalog Number:
E20-53067Amount:
100ulMolecular Weight:
199539DaApplications:
IHC-P;IF/ICCReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.Immunogen:
Synthetic Peptide of MAP2Source:
Monoclonal, Mouse
- Immunofluorescence analysis of Hela cell. 1,AQP2 Polyclonal Antibody(green) was diluted at 1:200(4° overnight). (red) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog:RS3211 was diluted at 1:1000(room temperature, 50min). Goat Anti Mouse Alexa Fluor 594 Catalog:RS3608 was diluted at 1:1000(room temperature, 50min).
Gene Name:
MAP2Dilution:
WB 500-2000 1:200 IF 1:50-200Background:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],Protein Name:
Microtubule-associated protein 2Human Gene Id:
4133Human Swiss Prot No:
P11137Mouse Swiss Prot No:
P20357Rat Swiss Prot No:
P15146Specificity:
The antibody detects endogenous MAP2 proteins.Formulation:
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.Storage Stability:
-20°C/1 yearOther Name:
MAP2; Microtubule-associated protein 2; MAP-2Function:
alternative products:Additional isoforms seem to exist,function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats.,Subcellular Location:
Cytoplasm, cytoskeleton . Cell projection, dendrite .Expression:
Brain,Brain cortex,Epithelium,Pancreas,Testis,
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