You are here: EnoGene Home > Products > Cell Signal Transduction Research Antibodies > Lamin B1 Monoclonal Antibody
Lamin B1 Monoclonal Antibody
Datasheet
Catalog Number:
E20-53036Amount:
100ulMolecular Weight:
66408DaApplications:
WB;IHC-p;IF/ICC;IPReactivity:
Human;Rat;MousePurification:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.Immunogen:
Recombinant Protein of Lamin-B1Source:
Monoclonal, Mouse
- 1) Input: Mouse Brain Tissue Lysate 2) IP product: IP dilute 1:200
Gene Name:
LMNB1Dilution:
WB: 1:2000-5000 IP:1:200 IF 1:200 IHC 1:50-300Background:
lamin B1(LMNB1) Homo sapiens This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],Protein Name:
Lamin-B1Human Gene Id:
4001Human Swiss Prot No:
P20700Mouse Gene Id:
16906Mouse Swiss Prot No:
P14733Rat Gene Id:
116685Rat Swiss Prot No:
P70615Specificity:
The antibody detects endogenous Lamin B1 protein.Formulation:
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.Storage Stability:
-20°C/1 yearOther Name:
LMNB1; LMN2; LMNB; Lamin-B1Observed Band(KD):
68Function:
disease:Defects in LMNB1 are the cause of leukodystrophy demyelinating autosomal dominant adult-onset (ADLD) [MIM:169500]. ADLD is a slowly progressive and fatal demyelinating leukodystrophy, presenting in the fourth or fifth decade of life. Clinically characterized by early autonomic abnormalities, pyramidal and cerebellar dysfunction, and symmetric demyelination of the CNS. It differs from multiple sclerosis and other demyelinating disorders in that neuropathology shows preservation of oligodendroglia in the presence of subtotal demyelination and lack of astrogliosis.,function:Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.,miscellaneous:The structural integrity of the lamina is strictly controlled by the cell cycleSubcellular Location:
Nucleus lamina .Expression:
Brain,Cajal-Retzius cell,Epithelium,Eye,Fetal brain cortex,Ovarian carcinoma,Placenta,Uterus,
Related Products
- PTEN (Phospho-Ser380) Antibody Datasheet
Catalog Number:
E011009-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
145$
- PTEN (Phospho-Ser380) Antibody Datasheet
Catalog Number:
E011009-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
225$
- NFκB-p65 (Phospho-Ser468) Antibody Datasheet
Catalog Number:
E011013-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
145$
- NFκB-p65 (Phospho-Ser468) Antibody Datasheet
Catalog Number:
E011013-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
225$
- Rel (Phospho-Ser503) Antibody Datasheet
Catalog Number:
E011020-1Amount:
50μg/50μlReactivity:
HumanApplications:
IF:1:100~1:200Swiss-Prot No.:
Q04864Price:
145$
Catalog Number
- Amount:100ul
- Price:225$
Contact us
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits