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COX IV Monoclonal Antibody
Datasheet   

  • Catalog Number:

    E20-53033
  • Amount:

    100ul
  • Molecular Weight:

    19577Da
  • Applications:

    WB;IHC-p;IF/ICC;
  • Reactivity:

    Human;Rat;Mouse
  • Purification:

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Immunogen:

    Recombinant Protein of Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
  • Source:

    Monoclonal, Mouse
  • Western blot analysis of Hela, diluted at 1) 1:2000 2) 1:5000
  • Gene Name:

    COX4I1
  • Dilution:

    WB: 1:1000-3000 IF 1:200 IHC 1:50-300
  • Background:

    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
  • Protein Name:

    Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
  • Human Gene Id:

    1327
  • Human Swiss Prot No:

    P13073
  • Mouse Gene Id:

    12857
  • Mouse Swiss Prot No:

    P19783
  • Rat Gene Id:

    29445
  • Rat Swiss Prot No:

    P10888
  • Specificity:

    The antibody detects endogenous COX IV protein.
  • Formulation:

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1
  • Observed Band(KD):

    15
  • Function:

    function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase IV family.,tissue specificity:Ubiquitous.,
  • Subcellular Location:

    Mitochondrion inner membrane ; Single-pass membrane protein .
  • Expression:

    Ubiquitous.

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Catalog Number

  • Amount:100ul
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Add to Cart

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