You are here: EnoGene Home > Products > Cell Signal Transduction Research Antibodies > Cleaved-ITI-H4 70k (R661) Polyclonal Antibody

Cleaved-ITI-H4 70k (R661) Polyclonal Antibody
Datasheet   MSDS

  • Catalog Number:

    E20-10095

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human ITIH4. AA range:612-661

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    ITIH4

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    inter-alpha-trypsin inhibitor heavy chain family member 4(ITIH4) Homo sapiens The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

  • Protein Name:

    Inter-alpha-trypsin inhibitor heavy chain H4

  • Human Gene Id:

    3700

  • Human Swiss Prot No:

    Q14624

  • Specificity:

    Cleaved-ITI-H4 70k (R661) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H4 70k protein resulting from cleavage adjacent to R661.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    ITIH4; IHRP; ITIHL1; PK120; Inter-alpha-trypsin inhibitor heavy chain H4; ITI heavy chain H4; ITI-HC4; Inter-alpha-inhibitor heavy chain 4; Inter-alpha-trypsin inhibitor family heavy chain-related protein; IHRP; Plasma kallikrein sensitive

  • MolecularWeight(Da):

    103325

  • Function:

    function:May be involved in acute phase reactions.,induction:Levels increase significantly in the sera of patients after different surgical trauma.,PTM:Appears to be both N- and O-glycosylated.,PTM:Cleaved by plasma kallikrein to yield 100 kDa and 35 kDa fragments, and the resulting 100 kDa fragment is further converted to a 70 kDa fragment.,PTM:The O-linked polysaccharides on Ser-696, Thr-701 and Ser-702 are probably the mucin type linked to GalNAc.,similarity:Belongs to the ITIH family.,similarity:Contains 1 VWFA domain.,tissue specificity:Liver specific.,

  • Subcellular Location:

    extracellular region,plasma membrane,platelet dense granule lumen,extracellular exosome,blood microparticle,

  • Expression:

    Fetal liver,Liver,Plasma,Pooled,Testicle,Ut

  • Immunohistochemical analysis of paraffin-embedded human tonsil. 1,Antibody was diluted overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3,Secondary antibody at 1:200(room temperature, 30min). For Research Use Only

Add to Cart

Related Products

PTEN (Phospho-Ser380) Antibody
PTEN (Phospho-Ser380) Antibody Datasheet  

  • Catalog Number:

    E011009-1

  • Amount:

    50μg/50μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    IHC: 1:50~1:100

  • Swiss-Prot No.:

    P60484

  • Price:

    145$
  • Add to Cart
PTEN (Phospho-Ser380) Antibody
PTEN (Phospho-Ser380) Antibody Datasheet  

  • Catalog Number:

    E011009-2

  • Amount:

    100μg/100μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    IHC: 1:50~1:100

  • Swiss-Prot No.:

    P60484

  • Price:

    225$
  • Add to Cart
NFκB-p65 (Phospho-Ser468) Antibody
NFκB-p65 (Phospho-Ser468) Antibody Datasheet  

  • Catalog Number:

    E011013-1

  • Amount:

    50μg/50μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    WB: 1:500~1:1000 IF:1:100~1:200

  • Swiss-Prot No.:

    Q04206

  • Price:

    145$
  • Add to Cart
NFκB-p65 (Phospho-Ser468) Antibody
NFκB-p65 (Phospho-Ser468) Antibody Datasheet  

  • Catalog Number:

    E011013-2

  • Amount:

    100μg/100μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    WB: 1:500~1:1000 IF:1:100~1:200

  • Swiss-Prot No.:

    Q04206

  • Price:

    225$
  • Add to Cart
Rel (Phospho-Ser503) Antibody
Rel (Phospho-Ser503) Antibody Datasheet  

  • Catalog Number:

    E011020-1

  • Amount:

    50μg/50μl

  • Reactivity:

    Human

  • Applications:

    IF:1:100~1:200

  • Swiss-Prot No.:

    Q04864

  • Price:

    145$
  • Add to Cart

Catalog Number

  • Amount:100ul
  • Price:225$

Add to Cart

AbPromise

Contact us

Cleaved-ITI-H4 70k (R661) Polyclonal Antibody | EnoGene Biotech Co. Ltd