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Cleaved-SUMO-2/3 (G93) Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-10075

  • Amount:

    100ul

  • Applications:

    WB;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human SUMO2/3. AA range:44-93

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using Cleaved-SUMO-2/3 (G93) Polyclonal Antibody

  • Gene Name:

    SUMO2

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

  • Background:

    This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Small ubiquitin-related modifier 2

  • Human Gene Id:

    6613

  • Human Swiss Prot No:

    P61956

  • Mouse Gene Id:

    170930

  • Mouse Swiss Prot No:

    P61957

  • Rat Gene Id:

    690244

  • Rat Swiss Prot No:

    P61959

  • Specificity:

    Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    SUMO2; SMT3A; SMT3H2; Small ubiquitin-related modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3AObserved Band:11KD

  • Function:

    function:Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.,online information:SUMO protein entry,PTM:Cleavage of precursor form by SENP1 or SENP2 is necessary for function.,PTM:Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function.,PTM:Polymeric chains can be formed through Lys-11 cross-linking.,similarity:Belongs to the ubiquitin family. S

  • Western blot analysis of lysates from HeLa cells, using SUMO2/3 (Cleaved-Gly93) Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
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Cleaved-SUMO-2/3 (G93) Polyclonal Antibody | EnoGene Biotech Co. Ltd