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Cleaved-Ephrin-A2 (N188) Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-10052
  • Amount:

    100ul
  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA
  • Reactivity:

    Human;Mouse
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EFNA2. AA range:139-188
  • Source:

    Polyclonal, Rabbit,IgG
  • Western Blot analysis of various cells using Cleaved-Ephrin-A2 (N188) Polyclonal Antibody
  • Gene Name:

    EFNA2
  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Background:

    This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008],
  • Protein Name:

    Ephrin-A2
  • Human Gene Id:

    1943
  • Human Swiss Prot No:

    O43921
  • Mouse Gene Id:

    13637
  • Mouse Swiss Prot No:

    P52801
  • Specificity:

    Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    EFNA2; EPLG6; LERK6; Ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-LObserved Band:21KD
  • Function:

    similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5.,
  • Subcellular Location:

    Cell membrane ; Lipid-anchor, GPI-anchor .
  • Expression:

    Brain,
  • Western blot analysis of lysates from 293 cells, treated with etoposide 25uM 1h, using EFNA2 (Cleaved-Asn188) Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
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