You are here: EnoGene Home > Products > Cell Signal Transduction Research Antibodies > Anti- p53 AntibodyPurified
Anti- p53 AntibodyPurified
Datasheet
Catalog Number:
E16THU001-050Amount:
50TestsForm of Antibody:
Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azideStorage/Stability:
Store at 4°C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.Background:
p53 is a 53 kD protein that forms tetramers and functions as a tumor suppressor and transcriptional activator of genes that inhibit growth and/or invasion, cell cycle checkpoint after irradiation, DNA repair, apoptotic induction, signal transduction, and cell adhesion. This protein is localized to the nucleus when activated and can be upregulated by genotoxic or other cellular stresses. p53 is modified by phosphorylation, acetylation, ribosylation, ubiquitination, and sumoylation; ubiquination targets p53 for degradation via mdm2. This protein interacts with a variety of proteins including mdm2, mdmx, topoisomerase I, PML3, Bcl-XL, Bcl-2, Chk1, JNK, p38, HIPK2, CK2, DNA-PK, p300/CBP, PCAF, PARP1, and HDAC1-3. Mutant p53 associates with p63 and p73.Isotype:
Mouse IgG2aClone Number:
4ABP53Reactivity:
Human,Not yet tested in other species.Applications:
WB；IHC
Under different test conditions, the best working concentration may be different, please work according to the results of preliminary experiments to determine the best concentration.
- MCF-7 cell extract was resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-p53 (clone 4ABP53-12) antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system
Price:
145$
Related Products
- PTEN (Phospho-Ser380) Antibody Datasheet
Catalog Number:
E011009-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
145$
- PTEN (Phospho-Ser380) Antibody Datasheet
Catalog Number:
E011009-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
225$
- NFκB-p65 (Phospho-Ser468) Antibody Datasheet
Catalog Number:
E011013-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
145$
- NFκB-p65 (Phospho-Ser468) Antibody Datasheet
Catalog Number:
E011013-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
225$
- Rel (Phospho-Ser503) Antibody Datasheet
Catalog Number:
E011020-1Amount:
50μg/50μlReactivity:
HumanApplications:
IF:1:100~1:200Swiss-Prot No.:
Q04864Price:
145$
Catalog Number
- Amount:50Tests
- Price:145$
Contact us
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits