Background:IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.
Product Information
Reconstitution:Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Shipping:The product is shipped with icepacks. Upon receipt, store it immediately at the temperature listed below.
DescriptionRecombinant Human Interleukin-1 Beta is produced by our E.coli expression system and the target gene encoding Ala117-Ser269 is expressed.Accession :P01584
Known as: Interleukin-1 beta; Catabolin; IL1F2; IL1B
Mol Mass:17.5kDa
AP Mol Mass:17kDa, reducing conditions.
Bioactivity: Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells. The ED50 for this effect is 20-100 pg/ml.
PurityGreater than 95% as determined by reducing SDS-PAGE.Fromulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 7.5.
Storage/StabilityLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.