RNF217 Antibody
Datasheet
Catalog Number:
E047802Amount:
100μg/100μlPrice:
255$Species:
RabbitAntibody type:
PolyclonalPurification:
Antigen affinity purificationApplications:
IHCRecommended Dilutions:
IHC dilution:1: 20-100Reactivity:
Hu, MsSpecificity/Sensitivity:
The antibody detects endogenous levels of total RNF217 protein.Gene Name:
RNF217Altername:
OSTL; IBRDC1; C6orf172; dJ84N20.1Immunogen:
Synthetic peptide of human RNF217Concentration:
0.9Form of Antibody:
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.Background:
This protein encoded by this gene is a member of the RING1-IBR-RING24 (RBR) ubiquitin protein ligase family, and it belongs to a subfamily of these proteins that contain a transmembrane domain. This protein can interact with the HAX1 anti-apoptotic protein via its C-terminal RING finger motif, which suggests a role in apoptosis signaling. It is thought that deregulation of this gene can be a mechanism in leukemogenesis. Mutations in the region encoding the protein GXXXG motif, which appears to be necessary for protein self-association, have been found in human cancers. Alternative splicing of this gene results in multiple transcript variants.?
Swiss-Prot No.:
Q8TC41Gene ID:
154214;
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Catalog Number
- Amount:100μg/100μl
- Price:255$
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