DAGLA Antibody
Datasheet
Catalog Number:
E047014Amount:
100μg/100μlPrice:
255$Species:
RabbitAntibody type:
PolyclonalPurification:
Antigen affinity purificationApplications:
IHCRecommended Dilutions:
Immunofluorescence:1: 25-100Reactivity:
HuSpecificity/Sensitivity:
The antibody detects endogenous levels of total DAGLA protein.Gene Name:
DAGLAAltername:
NSDDR; C11orf11; DAGLALPHA; DAGL(ALPHA)Immunogen:
Synthetic peptide of human DAGLAConcentration:
0.8mg/mlForm of Antibody:
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.Background:
Members of the AB hydrolase superfamily have diverse catalytic functions and play a crucial role in the metabolism of lipids. DAGLα (diacylglycerol lipase alpha), also known as NSDDR or C11orf11, is a 1,042 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. Highly expressed in brain and pancreas, DAGLα uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGLα functions as at optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2. The gene encoding DAGLα maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.Swiss-Prot No.:
Q9Y4D2Gene ID:
747;
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Catalog Number
- Amount:100μg/100μl
- Price:255$
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