Catalog Number:
E046993Amount:
100μg/100μlPrice:
255$Species:
RabbitAntibody type:
PolyclonalPurification:
Antigen affinity purificationApplications:
IHCRecommended Dilutions:
Reactivity:
HuSpecificity/Sensitivity:
The antibody detects endogenous levels of total CTNND2 protein.Gene Name:
CTNND2Altername:
GT24; NPRAPImmunogen:
Synthetic peptide of human CTNND2Concentration:
0.4mg/mlForm of Antibody:
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.Background:
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.Swiss-Prot No.:
Q9UQB3Gene ID:
1501;