Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark.
Product Information
ConjugationAF405M
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human Tau around the phosphorylation site of threonine 231 (V-R-TP-P-P)..
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityTau (Ab-231) antibody detects endogenous levels of total Tau protein.
ReferencesYen S.H.et.al. (1997) Neurochem. 69:1709-1719.
Beausoleil S.A.et.al. (2004) Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135.
Wintjens R.et.al. (2001) Biol. Chem. 276:25150-25156.
Babu J.R.et.al.(2005) Neurochem. 94:192-203.
Goedert M., Spillantini M.G. (2000) Biochim. Biophys. Acta 1502:110-121.
Western blot analysis of extract from mouse brain tissue using Tau (Ab-231) Antibody (E021099, Lane 1 and 2) and Tau (phospho- Thr231) antibody (E011110, Lane 3 and 4).