Form Or Antibody
Form of Antibodyintroduction: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Antibody typePrimary antibodyMark: Unconjugated
Antibody subtype: IgG1
PurificationAffinity purifiedReactive species: Human, Rat, Mouse
Gene NameBAXAlias: Apoptosis regulator bax, BAXA, BCL2 associated X protein
Swiss-Prot Acc.: Q07812
ImmunogenSynthetic peptide conjugated to KLH.
Product Information
Clone Number2F2-4G1-9G9
Molecular Weight(MW): 20kDaCell localization:Cytoplasm, Membrane, Mitochondrion
Storage/Stabilitysystem: PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.