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GDF-15 Polyclonal Antibody
：Human;Rat;Mouse;
：WB;ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameGDF15
Product Information
Protein NameGrowth/differentiation factor 15
Human Gene Id9518
Human Swiss Prot NoQ99988
Mouse Swiss Prot NoQ9Z0J7
SpecificityGDF-15 Polyclonal Antibody detects endogenous levels of GDF-15 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGDF15; MIC1; PDF; PLAB; PTGFB; Growth/differentiation factor 15; GDF-15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic
Molecular Weight34168DaObserved Band:37KD
Functionsimilarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.,
Subcellular LocationSecreted .
ExpressionHighly expressed in placenta, with lower levels in prostate and colon and some expression in kidney (PubMed:9348093). Detected in plasma (at protein level) (PubMed:28572090, PubMed:29046435).
ImmunogenThe antiserum was produced against synthesized peptide derived from human GDF15. AA range:31-80
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Backgroundgrowth differentiation factor 15(GDF15) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-71888-Conjugate. Price: $485 / Size: 100μl.
：E20-71888-FITC$485 / 100μl：E20-71888-Biotin$485 / 100μl：E20-71888-HRP$485 / 100μl：E20-71888-AP$485 / 100μl：E20-71888-AF350$485 / 100μl：E20-71888-AF405M$485 / 100μl：E20-71888-AF488$485 / 100μl：E20-71888-AF514$485 / 100μl：E20-71888-AF532$485 / 100μl：E20-71888-AF555$485 / 100μl：E20-71888-AF568$485 / 100μl：E20-71888-AF405S$485 / 100μl：E20-71888-AF405L$485 / 100μl：E20-71888-AF546$485 / 100μl：E20-71888-AF594$485 / 100μl：E20-71888-AF610$485 / 100μl：E20-71888-AF635$485 / 100μl：E20-71888-AF647$485 / 100μl：E20-71888-AF680$485 / 100μl：E20-71888-AF700$485 / 100μl：E20-71888-AF750$485 / 100μl：E20-71888-AF790$485 / 100μl：E20-71888-APC$485 / 100μl：E20-71888-PE$485 / 100μl：E20-71888-Cy3$485 / 100μl：E20-71888-Cy5$485 / 100μl：E20-71888-Cy5.5$485 / 100μl：E20-71888-Cy7$485 / 100μl：E20-71888-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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