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GCP4 Polyclonal Antibody
：Human;Mouse
：WB;IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameTUBGCP4
Product Information
Protein NameGamma-tubulin complex component 4
Human Gene Id27229
Human Swiss Prot NoQ9UGJ1
Mouse Gene Id51885
Mouse Swiss Prot NoQ9D4F8
SpecificityGCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTUBGCP4; 76P; GCP4; Gamma-tubulin complex component 4; GCP-4; hGCP4; Gamma-ring complex protein 76 kDa; h76p; hGrip76
Molecular Weight76089DaObserved Band:76KD
Functionfunction:Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.,similarity:Belongs to the GCP family.,subunit:Gamma-tubulin complex is composed of gamma-tubulin, GCP2, GCP3, GCP4, GCP5 and GCP6.,tissue specificity:Ubiquitously expressed.,
Subcellular LocationCytoplasm, cytoskeleton, microtubule organizing center, centrosome.
ExpressionUbiquitously expressed.
ImmunogenThe antiserum was produced against synthesized peptide derived from human TUBGCP4. AA range:191-240
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BackgroundThis gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-71880-Conjugate. Price: $485 / Size: 100μl.
：E20-71880-FITC$485 / 100μl：E20-71880-Biotin$485 / 100μl：E20-71880-HRP$485 / 100μl：E20-71880-AP$485 / 100μl：E20-71880-AF350$485 / 100μl：E20-71880-AF405M$485 / 100μl：E20-71880-AF488$485 / 100μl：E20-71880-AF514$485 / 100μl：E20-71880-AF532$485 / 100μl：E20-71880-AF555$485 / 100μl：E20-71880-AF568$485 / 100μl：E20-71880-AF405S$485 / 100μl：E20-71880-AF405L$485 / 100μl：E20-71880-AF546$485 / 100μl：E20-71880-AF594$485 / 100μl：E20-71880-AF610$485 / 100μl：E20-71880-AF635$485 / 100μl：E20-71880-AF647$485 / 100μl：E20-71880-AF680$485 / 100μl：E20-71880-AF700$485 / 100μl：E20-71880-AF750$485 / 100μl：E20-71880-AF790$485 / 100μl：E20-71880-APC$485 / 100μl：E20-71880-PE$485 / 100μl：E20-71880-Cy3$485 / 100μl：E20-71880-Cy5$485 / 100μl：E20-71880-Cy5.5$485 / 100μl：E20-71880-Cy7$485 / 100μl：E20-71880-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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