Product Information
Protein NameGuanylate-binding protein 3
Human Gene Id2635
Human Swiss Prot NoQ9H0R5
SpecificityGBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3
Molecular Weight64180DaObserved Band:64KD
Functionfunction:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,
Subcellular LocationCytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
ExpressionBrain,Prostate,
BackgroundThis gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],