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GBDR1 Polyclonal Antibody
：Human;Rat;Mouse;
：WB;IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameUBAC1
Product Information
Protein NameUbiquitin-associated domain-containing protein 1
Human Gene Id10422
Human Swiss Prot NoQ9BSL1
Mouse Swiss Prot NoQ8VDI7
SpecificityGBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameUBAC1; GBDR1; KPC2; UBADC1; Ubiquitin-associated domain-containing protein 1; UBA domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting com
Molecular Weight45338DaObserved Band:45KD
Functionfunction:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,
Subcellular LocationCytoplasm .
ExpressionUbiquitous.
ImmunogenThe antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Backgroundfunction:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,
Conjugated Antibody
This product is also available conjugated. Format: ：E20-71866-Conjugate. Price: $485 / Size: 100μl.
：E20-71866-FITC$485 / 100μl：E20-71866-Biotin$485 / 100μl：E20-71866-HRP$485 / 100μl：E20-71866-AP$485 / 100μl：E20-71866-AF350$485 / 100μl：E20-71866-AF405M$485 / 100μl：E20-71866-AF488$485 / 100μl：E20-71866-AF514$485 / 100μl：E20-71866-AF532$485 / 100μl：E20-71866-AF555$485 / 100μl：E20-71866-AF568$485 / 100μl：E20-71866-AF405S$485 / 100μl：E20-71866-AF405L$485 / 100μl：E20-71866-AF546$485 / 100μl：E20-71866-AF594$485 / 100μl：E20-71866-AF610$485 / 100μl：E20-71866-AF635$485 / 100μl：E20-71866-AF647$485 / 100μl：E20-71866-AF680$485 / 100μl：E20-71866-AF700$485 / 100μl：E20-71866-AF750$485 / 100μl：E20-71866-AF790$485 / 100μl：E20-71866-APC$485 / 100μl：E20-71866-PE$485 / 100μl：E20-71866-Cy3$485 / 100μl：E20-71866-Cy5$485 / 100μl：E20-71866-Cy5.5$485 / 100μl：E20-71866-Cy7$485 / 100μl：E20-71866-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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