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BRCAA1 Polyclonal Antibody
： Human;Mouse;Rat
： WB;ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene Name：ARID4B
Product Information
Protein Name：AT-rich interactive domain-containing protein 4B
Human Gene Id：51742
Human Swiss Prot No：Q4LE39
Mouse Gene Id：94246
Mouse Swiss Prot No：A2CG63
Rat Gene Id：84481
Rat Swiss Prot No：Q9JKB5
Specificity：BRCAA1 Polyclonal Antibody detects endogenous levels of BRCAA1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Hi
Molecular Weight：147809DaObserved Band：148KD
Function：domain:The ARID domain is involved in stabilizing the mSin3A corepressor complex on DNA.,domain:The C-terminus mediates interaction with mSin3A corepressor complex.,domain:The N-terminus is involved in transcriptional repression by HDAC-independent mechanisms.,function:Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.,similarity:Contains 1 ARID domain.,subcellular location:Cytoplasmic in breast cancer cells.,subunit:Component of a Sin3A corepressor complex consisting of SIN3A, SAP130, SUDS3/SAP45, SAP180, HDAC1 and HDAC2.,tissue specificity:Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.,
Subcellular Location：Nucleus . Cytoplasm . Cytoplasmic in breast cancer cells. .
Expression：Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary.
Immunogen：The antiserum was produced against synthesized peptide derived from human BRCAA1. AA range:761-810
Dilution：Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70521-Conjugate. Price: $485 / Size: 100μl.
：E20-70521-FITC$485 / 100μl：E20-70521-Biotin$485 / 100μl：E20-70521-HRP$485 / 100μl：E20-70521-AP$485 / 100μl：E20-70521-AF350$485 / 100μl：E20-70521-AF405M$485 / 100μl：E20-70521-AF488$485 / 100μl：E20-70521-AF514$485 / 100μl：E20-70521-AF532$485 / 100μl：E20-70521-AF555$485 / 100μl：E20-70521-AF568$485 / 100μl：E20-70521-AF405S$485 / 100μl：E20-70521-AF405L$485 / 100μl：E20-70521-AF546$485 / 100μl：E20-70521-AF594$485 / 100μl：E20-70521-AF610$485 / 100μl：E20-70521-AF635$485 / 100μl：E20-70521-AF647$485 / 100μl：E20-70521-AF680$485 / 100μl：E20-70521-AF700$485 / 100μl：E20-70521-AF750$485 / 100μl：E20-70521-AF790$485 / 100μl：E20-70521-APC$485 / 100μl：E20-70521-PE$485 / 100μl：E20-70521-Cy3$485 / 100μl：E20-70521-Cy5$485 / 100μl：E20-70521-Cy5.5$485 / 100μl：E20-70521-Cy7$485 / 100μl：E20-70521-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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