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BMP-8B Polyclonal Antibody
： Human;Rat;Mouse;
： WB;ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameBMP8B
Product Information
Protein NameBone morphogenetic protein 8B
Human Gene Id656
Human Swiss Prot NoP34820
Mouse Swiss Prot NoP55105
SpecificityBMP-8B Polyclonal Antibody detects endogenous levels of BMP-8B protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2
Molecular Weight44768DaObserved Band:45KD
Functionfunction:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 8b entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
Subcellular LocationSecreted .
ExpressionHippocampus,Testis,
ImmunogenThe antiserum was produced against synthesized peptide derived from human BMP8B. AA range:261-310
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BackgroundThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70506-Conjugate. Price: $485 / Size: 100μl.
：E20-70506-FITC$485 / 100μl：E20-70506-Biotin$485 / 100μl：E20-70506-HRP$485 / 100μl：E20-70506-AP$485 / 100μl：E20-70506-AF350$485 / 100μl：E20-70506-AF405M$485 / 100μl：E20-70506-AF488$485 / 100μl：E20-70506-AF514$485 / 100μl：E20-70506-AF532$485 / 100μl：E20-70506-AF555$485 / 100μl：E20-70506-AF568$485 / 100μl：E20-70506-AF405S$485 / 100μl：E20-70506-AF405L$485 / 100μl：E20-70506-AF546$485 / 100μl：E20-70506-AF594$485 / 100μl：E20-70506-AF610$485 / 100μl：E20-70506-AF635$485 / 100μl：E20-70506-AF647$485 / 100μl：E20-70506-AF680$485 / 100μl：E20-70506-AF700$485 / 100μl：E20-70506-AF750$485 / 100μl：E20-70506-AF790$485 / 100μl：E20-70506-APC$485 / 100μl：E20-70506-PE$485 / 100μl：E20-70506-Cy3$485 / 100μl：E20-70506-Cy5$485 / 100μl：E20-70506-Cy5.5$485 / 100μl：E20-70506-Cy7$485 / 100μl：E20-70506-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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