Product Information
Protein Name:Bone morphogenetic protein 8A
Human Gene Id:353500
Human Swiss Prot No:Q7Z5Y6
Mouse Swiss Prot No:P34821
Specificity:BMP-8A Polyclonal Antibody detects endogenous levels of BMP-8A protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Storage Stability:-20°C/1 year
Other Name:BMP8A; Bone morphogenetic protein 8A; BMP-8A
Molecular Weight:44798DaObserved Band:45KD
Function:function:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 8A entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
Subcellular Location:Secreted .
Expression:Brain,Hippocampus,Thyroid gland,
Background:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],