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BMP-2 Polyclonal Antibody
： Human;Mouse;Rat
： IF/ICC;WB;IHC-p;ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameBMP2
Product Information
Protein NameBone morphogenetic protein 2
Human Gene Id650
Human Swiss Prot NoP12643
Mouse Gene Id12156
Mouse Swiss Prot NoP21274
Rat Gene Id29373
Rat Swiss Prot NoP49001
SpecificityBMP-2 Polyclonal Antibody detects endogenous levels of BMP-2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A
Molecular Weight44702DaObserved Band:44KD
Functionfunction:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked. Interacts with GREM2 (By similarity) and SOSTDC1.,tissue specificity:Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.,
Subcellular LocationSecreted.
ExpressionParticularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
ImmunogenSynthesized peptide derived from Bone morphogenetic protein 2 at AA range: 341-390
DilutionIF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BackgroundThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70498-Conjugate. Price: $485 / Size: 100μl.
：E20-70498-FITC$485 / 100μl：E20-70498-Biotin$485 / 100μl：E20-70498-HRP$485 / 100μl：E20-70498-AP$485 / 100μl：E20-70498-AF350$485 / 100μl：E20-70498-AF405M$485 / 100μl：E20-70498-AF488$485 / 100μl：E20-70498-AF514$485 / 100μl：E20-70498-AF532$485 / 100μl：E20-70498-AF555$485 / 100μl：E20-70498-AF568$485 / 100μl：E20-70498-AF405S$485 / 100μl：E20-70498-AF405L$485 / 100μl：E20-70498-AF546$485 / 100μl：E20-70498-AF594$485 / 100μl：E20-70498-AF610$485 / 100μl：E20-70498-AF635$485 / 100μl：E20-70498-AF647$485 / 100μl：E20-70498-AF680$485 / 100μl：E20-70498-AF700$485 / 100μl：E20-70498-AF750$485 / 100μl：E20-70498-AF790$485 / 100μl：E20-70498-APC$485 / 100μl：E20-70498-PE$485 / 100μl：E20-70498-Cy3$485 / 100μl：E20-70498-Cy5$485 / 100μl：E20-70498-Cy5.5$485 / 100μl：E20-70498-Cy7$485 / 100μl：E20-70498-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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