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Blk Polyclonal Antibody
： Human;Mouse;Rat
：WB;IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameBLK
Product Information
Protein NameTyrosine-protein kinase Blk
Human Gene Id640
Human Swiss Prot NoP51451
Mouse Gene Id12143
Mouse Swiss Prot NoP16277
SpecificityBlk Polyclonal Antibody detects endogenous levels of Blk protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk
Molecular Weight57706DaObserved Band:58KD
Functioncatalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May function in a signal transduction pathway that is restricted to B-lymphoid cells.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,
Subcellular LocationCell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .
ExpressionExpressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands
ImmunogenThe antiserum was produced against synthesized peptide derived from human BLK. AA range:456-505
DilutionImmunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BackgroundThis gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70492-Conjugate. Price: $485 / Size: 100μl.
：E20-70492-FITC$485 / 100μl：E20-70492-Biotin$485 / 100μl：E20-70492-HRP$485 / 100μl：E20-70492-AP$485 / 100μl：E20-70492-AF350$485 / 100μl：E20-70492-AF405M$485 / 100μl：E20-70492-AF488$485 / 100μl：E20-70492-AF514$485 / 100μl：E20-70492-AF532$485 / 100μl：E20-70492-AF555$485 / 100μl：E20-70492-AF568$485 / 100μl：E20-70492-AF405S$485 / 100μl：E20-70492-AF405L$485 / 100μl：E20-70492-AF546$485 / 100μl：E20-70492-AF594$485 / 100μl：E20-70492-AF610$485 / 100μl：E20-70492-AF635$485 / 100μl：E20-70492-AF647$485 / 100μl：E20-70492-AF680$485 / 100μl：E20-70492-AF700$485 / 100μl：E20-70492-AF750$485 / 100μl：E20-70492-AF790$485 / 100μl：E20-70492-APC$485 / 100μl：E20-70492-PE$485 / 100μl：E20-70492-Cy3$485 / 100μl：E20-70492-Cy5$485 / 100μl：E20-70492-Cy5.5$485 / 100μl：E20-70492-Cy7$485 / 100μl：E20-70492-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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