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BCoR Polyclonal Antibody
：Human;Mouse
：WB;IHC-p;IF(paraffin section);ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene Name：BCOR
Product Information
Protein Name：BCL-6 corepressor
Human Gene Id：54880
Human Swiss Prot No：Q6W2J9
Mouse Gene Id：71458
Mouse Swiss Prot No：Q8CGN4
Specificity：BCoR Polyclonal Antibody detects endogenous levels of BCoR protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：BCOR; KIAA1575; BCL-6 corepressor; BCoR
Molecular Weight：192189DaObserved Band：192KD
Function：disease:Defects in BCOR are the cause of microphthalmia syndromic type 2 (MCOPS2) [MIM:300166]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS2 is a very rare multiple congenital anomaly syndrome characterized by eye anomalies (congenital cataract, microphthalmia, or secondary glaucoma), facial abnormalities (long narrow face, high nasal bridge, pointed nose with cartilages separated at the tip, cleft palate, or submucous cleft palate), cardiac anomalies (atrial septal defect, ventricular septal defect, or floppy mitral valve) and dental abnormalities (canine radiculomegaly, delayed dentition, oligodontia, persistent primary teeth, or var
Subcellular Location：Nucleus .
Expression：Ubiquitously expressed.
Immunogen：The antiserum was produced against synthesized peptide derived from human BCOR. AA range:1231-1280
Dilution：Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70480-Conjugate. Price: $485 / Size: 100μl.
：E20-70480-FITC$485 / 100μl：E20-70480-Biotin$485 / 100μl：E20-70480-HRP$485 / 100μl：E20-70480-AP$485 / 100μl：E20-70480-AF350$485 / 100μl：E20-70480-AF405M$485 / 100μl：E20-70480-AF488$485 / 100μl：E20-70480-AF514$485 / 100μl：E20-70480-AF532$485 / 100μl：E20-70480-AF555$485 / 100μl：E20-70480-AF568$485 / 100μl：E20-70480-AF405S$485 / 100μl：E20-70480-AF405L$485 / 100μl：E20-70480-AF546$485 / 100μl：E20-70480-AF594$485 / 100μl：E20-70480-AF610$485 / 100μl：E20-70480-AF635$485 / 100μl：E20-70480-AF647$485 / 100μl：E20-70480-AF680$485 / 100μl：E20-70480-AF700$485 / 100μl：E20-70480-AF750$485 / 100μl：E20-70480-AF790$485 / 100μl：E20-70480-APC$485 / 100μl：E20-70480-PE$485 / 100μl：E20-70480-Cy3$485 / 100μl：E20-70480-Cy5$485 / 100μl：E20-70480-Cy5.5$485 / 100μl：E20-70480-Cy7$485 / 100μl：E20-70480-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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