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BAM32 Polyclonal Antibody
： Human;Mouse
： WB;IHC-p;IF(paraffin section);ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene Name：DAPP1
Product Information
Protein Name：Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
Human Gene Id：27071
Human Swiss Prot No：Q9UN19
Mouse Gene Id：26377
Mouse Swiss Prot No：Q9QXT1
Specificity：BAM32 Polyclonal Antibody detects endogenous levels of BAM32 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：DAPP1; BAM32; HSPC066; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa
Molecular Weight：32194DaObserved Band：32KD
Function：function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
Subcellular Location：Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
Expression：Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Immunogen：The antiserum was produced against synthesized peptide derived from human DAPP1. AA range:105-154
Dilution：Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70450-Conjugate. Price: $485 / Size: 100μl.
：E20-70450-FITC$485 / 100μl：E20-70450-Biotin$485 / 100μl：E20-70450-HRP$485 / 100μl：E20-70450-AP$485 / 100μl：E20-70450-AF350$485 / 100μl：E20-70450-AF405M$485 / 100μl：E20-70450-AF488$485 / 100μl：E20-70450-AF514$485 / 100μl：E20-70450-AF532$485 / 100μl：E20-70450-AF555$485 / 100μl：E20-70450-AF568$485 / 100μl：E20-70450-AF405S$485 / 100μl：E20-70450-AF405L$485 / 100μl：E20-70450-AF546$485 / 100μl：E20-70450-AF594$485 / 100μl：E20-70450-AF610$485 / 100μl：E20-70450-AF635$485 / 100μl：E20-70450-AF647$485 / 100μl：E20-70450-AF680$485 / 100μl：E20-70450-AF700$485 / 100μl：E20-70450-AF750$485 / 100μl：E20-70450-AF790$485 / 100μl：E20-70450-APC$485 / 100μl：E20-70450-PE$485 / 100μl：E20-70450-Cy3$485 / 100μl：E20-70450-Cy5$485 / 100μl：E20-70450-Cy5.5$485 / 100μl：E20-70450-Cy7$485 / 100μl：E20-70450-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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