World supplier of antibodies, antigens and kits since 2007
Other Products
Bak Polyclonal Antibody
： Human;Mouse
： WB;IHC-p;IF/ICC;ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene Name：BAK1
Product Information
Protein Name：Bcl-2 homologous antagonist/killer
Human Gene Id：578
Human Swiss Prot No：Q16611
Mouse Swiss Prot No：O08734
Specificity：Bak Polyclonal Antibody detects endogenous levels of Bak protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
Molecular Weight：23409DaObserved Band：25KD
Function：caution:Could be the product of a pseudogene.,domain:Intact BH3 domain is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family. Apoptotic members of the Bcl-2 family.,domain:Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.,function:In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the a repressor Bcl-2 or its adenovirus homolog E1B 19k protein.,function:In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the a. repressor BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.,similarity:Belongs to the B
Subcellular Location：Mitochondrion outer membrane ; Single-pass membrane protein .
Expression：Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Immunogen：The antiserum was produced against synthesized peptide derived from human Bak. AA range:1-50
Dilution：Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70449-Conjugate. Price: $485 / Size: 100μl.
：E20-70449-FITC$485 / 100μl：E20-70449-Biotin$485 / 100μl：E20-70449-HRP$485 / 100μl：E20-70449-AP$485 / 100μl：E20-70449-AF350$485 / 100μl：E20-70449-AF405M$485 / 100μl：E20-70449-AF488$485 / 100μl：E20-70449-AF514$485 / 100μl：E20-70449-AF532$485 / 100μl：E20-70449-AF555$485 / 100μl：E20-70449-AF568$485 / 100μl：E20-70449-AF405S$485 / 100μl：E20-70449-AF405L$485 / 100μl：E20-70449-AF546$485 / 100μl：E20-70449-AF594$485 / 100μl：E20-70449-AF610$485 / 100μl：E20-70449-AF635$485 / 100μl：E20-70449-AF647$485 / 100μl：E20-70449-AF680$485 / 100μl：E20-70449-AF700$485 / 100μl：E20-70449-AF750$485 / 100μl：E20-70449-AF790$485 / 100μl：E20-70449-APC$485 / 100μl：E20-70449-PE$485 / 100μl：E20-70449-Cy3$485 / 100μl：E20-70449-Cy5$485 / 100μl：E20-70449-Cy5.5$485 / 100μl：E20-70449-Cy7$485 / 100μl：E20-70449-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Primary Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- ELISA Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits
- Overexpression Cell Lines
- Cell Lysates
- Purification Resins
- 2019-nCoV & Monkeypox