Product Information
Protein Name:Transcription regulator protein BACH1
Human Gene Id:571
Human Swiss Prot No:O14867
Mouse Swiss Prot No:P97302
Specificity:BACH1 Polyclonal Antibody detects endogenous levels of BACH1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Storage Stability:-20°C/1 year
Other Name:BACH1; Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303
Molecular Weight:81958DaObserved Band:100KD
Function:function:Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,
Subcellular Location:Nucleus .
Expression:Epithelium,Placenta,Trachea,
Background:This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009],