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ATF-5 Polyclonal Antibody
： Human;Rat;Mouse;
： WB;IHC-p;IF(paraffin section);ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene Name：ATF5
Product Information
Protein Name：Cyclic AMP-dependent transcription factor ATF-5
Human Gene Id：22809
Human Swiss Prot No：Q9Y2D1
Mouse Gene Id：107503
Mouse Swiss Prot No：O70191
Rat Gene Id：282840
Rat Swiss Prot No：Q6P788
Specificity：ATF-5 Polyclonal Antibody detects endogenous levels of ATF-5 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx
Molecular Weight：30690DaObserved Band：31KD
Function：function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,
Subcellular Location：Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. .
Expression：Widely expressed with higher expression levels in liver.
Immunogen：The antiserum was produced against synthesized peptide derived from human ATF5. AA range:221-270
Dilution：Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70388-Conjugate. Price: $485 / Size: 100μl.
：E20-70388-FITC$485 / 100μl：E20-70388-Biotin$485 / 100μl：E20-70388-HRP$485 / 100μl：E20-70388-AP$485 / 100μl：E20-70388-AF350$485 / 100μl：E20-70388-AF405M$485 / 100μl：E20-70388-AF488$485 / 100μl：E20-70388-AF514$485 / 100μl：E20-70388-AF532$485 / 100μl：E20-70388-AF555$485 / 100μl：E20-70388-AF568$485 / 100μl：E20-70388-AF405S$485 / 100μl：E20-70388-AF405L$485 / 100μl：E20-70388-AF546$485 / 100μl：E20-70388-AF594$485 / 100μl：E20-70388-AF610$485 / 100μl：E20-70388-AF635$485 / 100μl：E20-70388-AF647$485 / 100μl：E20-70388-AF680$485 / 100μl：E20-70388-AF700$485 / 100μl：E20-70388-AF750$485 / 100μl：E20-70388-AF790$485 / 100μl：E20-70388-APC$485 / 100μl：E20-70388-PE$485 / 100μl：E20-70388-Cy3$485 / 100μl：E20-70388-Cy5$485 / 100μl：E20-70388-Cy5.5$485 / 100μl：E20-70388-Cy7$485 / 100μl：E20-70388-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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