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Asf1a Polyclonal Antibody

：E20-70368DatasheetCOAMSDS
： Human;Mouse;
： WB;IF/ICC;ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Gene Name：ASF1A

Product Information

Protein Name：Histone chaperone ASF1A
Human Gene Id：25842
Human Swiss Prot No：Q9Y294
Mouse Gene Id：66403
Mouse Swiss Prot No：Q9CQE6
Specificity：Asf1a Polyclonal Antibody detects endogenous levels of Asf1a protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：ASF1A; CGI-98; HSPC146; Histone chaperone ASF1A; Anti-silencing function protein 1 homolog A; hAsf1; hAsf1a; CCG1-interacting factor A; CIA; hCIA
Molecular Weight：22969DaObserved Band：23KD
Function：function:Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.,PTM:Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.,similarity:Belongs to the ASF1 family.,subunit:Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with CABIN1, HAT1, HIRA, NASP, TAF1, TLK1, TLK2 and UBN1.,tissue specificity:Ubiquitously expressed.,
Subcellular Location：Nucleus .
Expression：Ubiquitously expressed.
Immunogen：The antiserum was produced against synthesized peptide derived from human ASF1A. AA range:121-170
Dilution：Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The protein is a key component of a histone donor complex that functions in nucleosome assembly. It interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair. [provided by RefSeq, Jul 2008],
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: ：E20-70368-Conjugate. Price: $485 / Size: 100μl.

：E20-70368-FITC$485 / 100μl：E20-70368-Biotin$485 / 100μl：E20-70368-HRP$485 / 100μl：E20-70368-AP$485 / 100μl：E20-70368-AF350$485 / 100μl：E20-70368-AF405M$485 / 100μl：E20-70368-AF488$485 / 100μl：E20-70368-AF514$485 / 100μl：E20-70368-AF532$485 / 100μl：E20-70368-AF555$485 / 100μl：E20-70368-AF568$485 / 100μl：E20-70368-AF405S$485 / 100μl：E20-70368-AF405L$485 / 100μl：E20-70368-AF546$485 / 100μl：E20-70368-AF594$485 / 100μl：E20-70368-AF610$485 / 100μl：E20-70368-AF635$485 / 100μl：E20-70368-AF647$485 / 100μl：E20-70368-AF680$485 / 100μl：E20-70368-AF700$485 / 100μl：E20-70368-AF750$485 / 100μl：E20-70368-AF790$485 / 100μl：E20-70368-APC$485 / 100μl：E20-70368-PE$485 / 100μl：E20-70368-Cy3$485 / 100μl：E20-70368-Cy5$485 / 100μl：E20-70368-Cy5.5$485 / 100μl：E20-70368-Cy7$485 / 100μl：E20-70368-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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