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Arp3 Polyclonal Antibody
： Human;Mouse;Rat
： WB;ELISA
：Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene Name：ACTR3
Product Information
Protein Name：Actin-related protein 3
Human Gene Id：10096
Human Swiss Prot No：P61158
Mouse Gene Id：74117
Mouse Swiss Prot No：Q99JY9
Rat Gene Id：81732
Rat Swiss Prot No：Q4V7C7
Specificity：Arp3 Polyclonal Antibody detects endogenous levels of Arp3 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration：1 mg/ml
Storage Stability：-20°C/1 year
Other Name：ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3
Molecular Weight：47371DaObserved Band：47KD
Function：function:Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.,similarity:Belongs to the actin family.,similarity:Belongs to the actin family. ARP3 subfamily.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1.,
Subcellular Location：Cytoplasm, cytoskeleton . Cell projection . Nucleus . In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554).
Expression：Brain,Cajal-Retzius cell,T-cell,
Immunogen：The antiserum was produced against synthesized peptide derived from human ACTR3. AA range:369-418
Dilution：Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background：The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013],
Conjugated Antibody
This product is also available conjugated. Format: ：E20-70336-Conjugate. Price: $485 / Size: 100μl.
：E20-70336-FITC$485 / 100μl：E20-70336-Biotin$485 / 100μl：E20-70336-HRP$485 / 100μl：E20-70336-AP$485 / 100μl：E20-70336-AF350$485 / 100μl：E20-70336-AF405M$485 / 100μl：E20-70336-AF488$485 / 100μl：E20-70336-AF514$485 / 100μl：E20-70336-AF532$485 / 100μl：E20-70336-AF555$485 / 100μl：E20-70336-AF568$485 / 100μl：E20-70336-AF405S$485 / 100μl：E20-70336-AF405L$485 / 100μl：E20-70336-AF546$485 / 100μl：E20-70336-AF594$485 / 100μl：E20-70336-AF610$485 / 100μl：E20-70336-AF635$485 / 100μl：E20-70336-AF647$485 / 100μl：E20-70336-AF680$485 / 100μl：E20-70336-AF700$485 / 100μl：E20-70336-AF750$485 / 100μl：E20-70336-AF790$485 / 100μl：E20-70336-APC$485 / 100μl：E20-70336-PE$485 / 100μl：E20-70336-Cy3$485 / 100μl：E20-70336-Cy5$485 / 100μl：E20-70336-Cy5.5$485 / 100μl：E20-70336-Cy7$485 / 100μl：E20-70336-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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