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IL6 Antibody (Center)
Datasheet   

  • Catalog Number:

    E45R07986G-1

  • Amount:

    100 µl

  • Cite ID#:

    EN5480798

  • Price:

    395$

  • Type:

    Rabbit Polyclonal Antibody

  • Host:

    Rabbit

  • Reactivity:

    H

  • Immunogen:

    This IL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the Central region of human IL6.

  • Purification:

    Affinity chromatography purified.

  • Gene Name:

    IL6 (HGNC:6018)

  • Gene ID:

    3569

  • Swiss-Prot No.:

    P05231

  • Function:

    Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans- signaling'. Alternatively, 'cluster signaling' occurs when membrane- bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).

  • Summary:

    Tissue Location:
    Produced by skeletal muscle.

  • Form:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

  • Storage/Stability:

    For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Applications:

    FC, IHC-P, WB

  • Dilution:

    WB--1:1000
    FC--1:10~50
    IHC-P--1:100~500

  • Altername:

    Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2

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  • Amount:100 µl
  • Price:395.00$

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