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MME Antibody (Center)
Datasheet   

  • Catalog Number:

    E45R03424G-4

  • Amount:

    50 µl

  • Cite ID#:

    EN5469679

  • Price:

    295$

  • Type:

    Rabbit Polyclonal Antibody

  • Host:

    Rabbit

  • Reactivity:

    H, M

  • Immunogen:

    This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-747 amino acids from the C-terminal region of human MME.

  • Purification:

    Affinity chromatography purified.

  • Gene Name:

    MME

  • Gene ID:

    4311

  • Swiss-Prot No.:

    P08473

  • Function:

    Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1- 32)) (PubMed:2531377, PubMed:2972276, PubMed:16254193). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).

  • Form:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

  • Storage/Stability:

    For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Applications:

    IHC-P, WB

  • Dilution:

    WB--1:1000
    IHC-P--1:100~500

  • Altername:

    Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 2411, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN

  • Synonyms:

    Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 2411, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN

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  • Amount:50 µl
  • Price:295.00$

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