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B7-2 (CD86) Mouse Monoclonal Antibody [Clone 20F11]
Datasheet   

  • Catalog Number:

    E45M21027V-2

  • Amount:

    50 ul

  • Cite ID#:

    EN5457182

  • Price:

    195$

  • Type:

    Mouse Monoclonal Antibody

  • Research Field:

    Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

  • Product Description:

    CD86 mouse monoclonal antibody,Clone 20F11

  • Host:

    Mouse

  • Reactivity:

    Human

  • Immunogen:

    Full length human recombinant protein of human CD86 (NP_787058) produced in HEK293T cell.

  • Target:

    CD86

  • Clone Number:

    Clone 20F11

  • Isotype:

    IgG1

  • Purification:

    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

  • Gene Name:

    CD86 molecule

  • Gene symbol:

    CD86

  • Gene ID:

    942

  • Swiss-Prot No.:

    P42081

  • Pathway:

    Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

  • Function:

    Druggable Genome, Transcription Factors, Transmembrane

  • Summary:

    This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2011]

  • Form:

    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage/Stability:

    Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

  • Applications:

    WB 1:1000

  • Synonyms:

    B7-2; B7.2; B70; CD28LG2; LAB72

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