Catalog Number:
E45M20418V-2Amount:
50 ulCite ID#:
EN5456573Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
FANCC mouse monoclonal antibody,Clone 8A7Host:
MouseReactivity:
HumanImmunogen:
Human recombinant protein fragment corresponding to amino acids 1-284 of human FANCC (NP_000127) produced in E.coli.Target:
FANCCClone Number:
Clone 8A7Isotype:
IgG2aPurification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
Fanconi anemia complementation group CGene symbol:
FANCCGene ID:
2176Swiss-Prot No.:
Q00597Function:
Druggable GenomeSummary:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:2000Synonyms:
FA3; FAC; FACC