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PCDHGC5 Mouse Monoclonal Antibody [Clone 1A6]
Datasheet   

  • Catalog Number:

    E45M18007V-2
  • Amount:

    50 ul
  • Cite ID#:

    EN5454162
  • Price:

    195$
  • Type:

    Mouse Monoclonal Antibody
  • Product Description:

    PCDHGC5 mouse monoclonal antibody, Clone 1A6
  • Host:

    Mouse
  • Reactivity:

    Human, Mouse, Rat
  • Immunogen:

    Human recombinant protein fragment corresponding to amino acids 35-258 of human PCDHGC5(NP_115783) produced in E.coli.
  • Target:

    PCDHGC5
  • Clone Number:

    Clone 1A6
  • Isotype:

    IgG1
  • Purification:

    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
  • Gene Name:

    protocadherin gamma subfamily C, 5
  • Gene symbol:

    PCDHGC5
  • Gene ID:

    56097
  • Swiss-Prot No.:

    Q9Y5F6
  • Function:

    Transmembrane
  • Summary:

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul
  • Form:

    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage/Stability:

    Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
  • Applications:

    WB 1:2000
  • Synonyms:

    PCDH-GAMMA-C5

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