Catalog Number:
E45M18007V-2Amount:
50 ulCite ID#:
EN5454162Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
PCDHGC5 mouse monoclonal antibody, Clone 1A6Host:
MouseReactivity:
Human, Mouse, RatImmunogen:
Human recombinant protein fragment corresponding to amino acids 35-258 of human PCDHGC5(NP_115783) produced in E.coli.Target:
PCDHGC5Clone Number:
Clone 1A6Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
protocadherin gamma subfamily C, 5Gene symbol:
PCDHGC5Gene ID:
56097Swiss-Prot No.:
Q9Y5F6Function:
TransmembraneSummary:
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, JulForm:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:2000Synonyms:
PCDH-GAMMA-C5