Catalog Number:
E45M16880Amount:
100 ugCite ID#:
EN5458953Price:
595$Type:
Mouse Monoclonal AntibodyProduct Description:
Carrier-free (BSA/glycerol-free) HDAC9 mouse monoclonal antibody, clone LBI5B8Host:
MouseReactivity:
Human, Mouse, RatImmunogen:
Human recombinant protein fragment corresponding to amino acids 181-460 of human HDAC9 (NP_055522) produced in E.coli.Target:
HDAC9Conjugation:
UnconjugatedClone Number:
Clone:5B8Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
Homo sapiens histone deacetylase 9 (HDAC9), transcript variant 3, mRNA.Gene symbol:
HDAC9Gene ID:
9734Swiss-Prot No.:
Q9UKV0Function:
Druggable Genome, Transcription FactorsSummary:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]Form:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)Storage/Stability:
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Storage Buffer:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)Applications:
WB 1:2000, IHC 1:150Synonyms:
HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; MITR