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p95 NBS1 (NBN) Mouse Monoclonal Antibody [Clone:6D10]
Datasheet   

  • Catalog Number:

    E45M15071

  • Amount:

    100 ug

  • Cite ID#:

    EN5467649

  • Price:

    595$

  • Type:

    Mouse Monoclonal Antibody

  • Research Field:

    Homologous recombination

  • Product Description:

    Carrier-free (BSA/glycerol-free) NBN mouse monoclonal antibody, clone LBI6D10

  • Host:

    Mouse

  • Reactivity:

    Human

  • Immunogen:

    Human recombinant protein fragment corresponding to amino acids 183-460 of human NBN (NP_002476) produced in E.coli.

  • Target:

    NBN

  • Conjugation:

    Unconjugated

  • Clone Number:

    Clone:6D10

  • Isotype:

    IgG1

  • Purification:

    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

  • Gene Name:

    Homo sapiens nibrin (NBN), transcript variant 1, mRNA.

  • Gene symbol:

    NBN

  • Gene ID:

    4683

  • Swiss-Prot No.:

    O60934

  • Pathway:

    Homologous recombination

  • Function:

    Druggable Genome

  • Summary:

    Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

  • Form:

    Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

  • Storage/Stability:

    Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

  • Applications:

    WB 1:2000, IHC 1:150

  • Synonyms:

    AT-V1; AT-V2; ATV; NBS; NBS1; P95

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  • Amount:100 ug
  • Price:595.00$

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