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NM23A (NME1) Mouse Monoclonal Antibody [Clone 1C12]
Datasheet   

  • Catalog Number:

    E45M15015V-2

  • Amount:

    50 ul

  • Cite ID#:

    EN5451170

  • Price:

    195$

  • Type:

    Mouse Monoclonal Antibody

  • Research Field:

    Metabolic pathways, Purine metabolism, Pyrimidine metabolism

  • Product Description:

    NME1 mouse monoclonal antibody, Clone 1C12

  • Host:

    Mouse

  • Reactivity:

    Human, Mouse, Rat

  • Immunogen:

    Full length human recombinant protein of human NME1 (NP_937818) produced in E.coli.

  • Target:

    NME1

  • Clone Number:

    Clone 1C12

  • Isotype:

    IgG1

  • Purification:

    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

  • Gene Name:

    NME/NM23 nucleoside diphosphate kinase 1

  • Gene symbol:

    NME1

  • Gene ID:

    4830

  • Swiss-Prot No.:

    P15531

  • Pathway:

    Metabolic pathways, Purine metabolism, Pyrimidine metabolism

  • Function:

    Druggable Genome, Stem cell - Pluripotency

  • Summary:

    This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

  • Form:

    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage/Stability:

    Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

  • Applications:

    WB 1:2000, IHC 1:150

  • Synonyms:

    AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1

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