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p18 INK4c (CDKN2C) Mouse Monoclonal Antibody [Clone:1E4]
Datasheet   

  • Catalog Number:

    E45M14969

  • Amount:

    100 ug

  • Cite ID#:

    EN5467547

  • Price:

    595$

  • Type:

    Mouse Monoclonal Antibody

  • Research Field:

    Cell cycle

  • Product Description:

    Carrier-free (BSA/glycerol-free) CDKN2C mouse monoclonal antibody, clone LBI1E4

  • Host:

    Mouse

  • Reactivity:

    Human, Mouse, Rat

  • Immunogen:

    Full length human recombinant protein of human CDKN2C (NP_001253) produced in E.coli.

  • Target:

    CDKN2C

  • Conjugation:

    Unconjugated

  • Clone Number:

    Clone:1E4

  • Isotype:

    IgG1

  • Purification:

    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

  • Gene Name:

    Homo sapiens cyclin dependent kinase inhibitor 2C (CDKN2C), transcript variant 1, mRNA.

  • Gene symbol:

    CDKN2C

  • Gene ID:

    1031

  • Swiss-Prot No.:

    P42773

  • Pathway:

    Cell cycle

  • Function:

    Druggable Genome

  • Summary:

    The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]

  • Form:

    Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

  • Storage/Stability:

    Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

  • Applications:

    WB 1:2000

  • Synonyms:

    INK4C; p18; p18-INK4C

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  • Amount:100 ug
  • Price:595.00$

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