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CDC45L (CDC45) (NM_003504) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H40864M5

  • Amount:

    20 ug

  • Cite ID#:

    EN5443295

  • Price:

    785$

  • Type:

    Recombinant Proteins

  • Research Field:

    Cell cycle

  • Product Description:

    Recombinant protein of human CDC45 cell division cycle 45-like (S. cerevisiae) (CDC45L)

  • Protein length:

    Recombinant protein was produced with GoldORF clone, [GH32413V]. Click on the GoldORF clone link to view cDNA and protein sequences.

  • Expression Host:

    HEK293T

  • Species:

    Human

  • Molecular Weight:

    65.4 kDa

  • Gene symbol:

    CDC45

  • Gene ID:

    8318

  • mRNA Refseq:

    NM_003504

  • Protein Refseq:

    NP_003495

  • Swiss-Prot No.:

    O75419

  • Chromosome location:

    22q11.21

  • Pathway:

    Cell cycle

  • Function:

    Druggable Genome, Stem cell - Pluripotency

  • Summary:

    The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

  • Form:

    Liquid

  • Concentration:

    >50 ug/mL as determined by microplate BCA method

  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining

  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

  • Synonyms:

    CDC45L; CDC45L2; MGORS7; PORC-PI-1

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  • Amount:20 ug
  • Price:785.00$

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