You are here: EnoGene Home > Products > MPZL (MPZL1) (NM_003953) Human Recombinant Protein

MPZL (MPZL1) (NM_003953) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H40490M5

  • Amount:

    20 ug

  • Cite ID#:

    EN5442921

  • Price:

    785$

  • Type:

    Recombinant Proteins

  • Research Field:

    Cell adhesion molecules (CAMs)

  • Product Description:

    Recombinant protein of human myelin protein zero-like 1 (MPZL1), transcript variant 1

  • Protein length:

    Recombinant protein was produced with GoldORF clone, [GH33135V]. Click on the GoldORF clone link to view cDNA and protein sequences.

  • Expression Host:

    HEK293T

  • Species:

    Human

  • Molecular Weight:

    28.9 kDa

  • Gene symbol:

    MPZL1

  • Gene ID:

    9019

  • mRNA Refseq:

    NM_003953

  • Protein Refseq:

    NP_003944

  • Swiss-Prot No.:

    O95297, A8K5D4

  • Chromosome location:

    1q24.2

  • Pathway:

    Cell adhesion molecules (CAMs)

  • Function:

    Druggable Genome, Transmembrane

  • Summary:

    Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.[UniProtKB/Swiss-Prot Function]

  • Form:

    Liquid

  • Concentration:

    >50 ug/mL as determined by microplate BCA method

  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining

  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

  • Synonyms:

    MPZL1b; PZR; PZR1b; PZRa; PZRb

Related Products

Catalog Number

  • Amount:20 ug
  • Price:785.00$

AbPromise

Contact us