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CRMP2 (DPYSL2) (NM_001386) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H37809M5

  • Amount:

    20 ug

  • Cite ID#:

    EN5440241

  • Price:

    785$

  • Type:

    Recombinant Proteins

  • Research Field:

    Axon guidance

  • Product Description:

    Purified recombinant protein of Homo sapiens dihydropyrimidinase-like 2 (DPYSL2)

  • Protein length:

    Recombinant protein was produced with GoldORF clone, [GH38932V]. Click on the GoldORF clone link to view cDNA and protein sequences.

  • Expression Host:

    HEK293T

  • Species:

    Human

  • Molecular Weight:

    62.1 kDa

  • Activity:

    WB positive control (PMID: 29774780)

  • Gene symbol:

    DPYSL2

  • Gene ID:

    1808

  • mRNA Refseq:

    NM_001386

  • Protein Refseq:

    NP_001377

  • Swiss-Prot No.:

    Q16555

  • Chromosome location:

    8p21.2

  • Pathway:

    Axon guidance

  • Function:

    Druggable Genome

  • Summary:

    This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

  • Form:

    Liquid

  • Concentration:

    >50 ug/mL as determined by microplate BCA method

  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining

  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

  • Synonyms:

    CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2

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  • Amount:20 ug
  • Price:785.00$

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