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CARS1 (NM_001014437) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H33844M5

  • Amount:

    20 ug

  • Cite ID#:

    EN5436279

  • Price:

    785$

  • Type:

    Recombinant Proteins

  • Research Field:

    Aminoacyl-tRNA biosynthesis

  • Product Description:

    Recombinant protein of human cysteinyl-tRNA synthetase (CARS), transcript variant 3

  • Protein length:

    Recombinant protein was produced with GoldORF clone, [GH53248V]. Click on the GoldORF clone link to view cDNA and protein sequences.

  • Expression Host:

    HEK293T

  • Species:

    Human

  • Molecular Weight:

    94.5 kDa

  • Gene symbol:

    CARS

  • Gene ID:

    833

  • mRNA Refseq:

    NM_001014437

  • Protein Refseq:

    NP_001014437

  • Swiss-Prot No.:

    P49589

  • Chromosome location:

    11p15.4

  • Pathway:

    Aminoacyl-tRNA biosynthesis

  • Function:

    Druggable Genome

  • Summary:

    This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]

  • Form:

    Liquid

  • Concentration:

    >50 ug/mL as determined by microplate BCA method

  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining

  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

  • Synonyms:

    CARS1; CYSRS; MGC:11246

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  • Amount:20 ug
  • Price:785.00$

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